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Proteintech
EIF3D Polyclonal Antibody
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FIGURE: 1 / 18
EIF3D Antibody (10219-1-AP) in ICC/IF
IF result of 10219-1-AP (anti-EIF3D) in U2OS cell (treated with 100 mM sodium arsenite to cause stress-induced translational arrest) by Dr. Nancy Kedersha.U2OS cells (FAST-YFP stables; but not showing FAST-YFP); stained with PTG anti-eIF3p66 in green; and counterstained with anti-eIF3b (goat polyclonal) in red; nuclei stained blue using Hoechst.
Product Details
10219-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Yeast
Published species
Human,
Mouse,
Rabbit,
Yeast
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EIF3D Fusion Protein Ag0268 (323-531 aa encoded by BC000328)
Conjugate
Form
Liquid
Concentration
0.29 mg/mL
Amount
43.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FSQQCLRMG KERYNFPNPN PFVEDDMDKN EIASVAYRYR RWKLGDDIDL IVRCEHDGVM TGANGEVSFI NIKTLNEWDS RHCNGVDWRQ KLDSQRGAVI ATELKNNSYK LARWTCCALL AGSEYLKLGY VSRYHVKDSS RHVILGTQQF KPNEFASQIN LSVENAWGIL RCVIDICMKL EEGKYLILKD PNKQVIRVYS LPDGTFSSDE (323-531 aa encoded by BC000328)
Target Information
eIF3D is a protein belonging to the largest of the eukaryotic translation initiation factor family, eukaryotic translation initiation factor-3 (eIF3). eIF3 is a multiprotein complex composed of at least 13 different subunits. eIF3D binds to the 40S ribosomal subunit and thus helps in maintaining the 40S and 60S ribosomal subunits in a dissociated state. An important role of eIF3D is the formation of the 40S initiation complex by interacting with the ternary complex of eIF2/GTP/methionyl-tRNA, and promotes mRNA binding. eIF3D is the major RNA binding subunit of the eIF3 complex. It associates with the subunit p170 of eIF-3. Ubiquitous expression of eIF3D is seen in most of the tissues and it is phosphorylated upon DNA damage, likely by ATM or ATR.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: eIF-3-zeta; eIF3 p66; eIF3-p66; eIF3d; EIF3S7; Eukaryotic translation initiation factor 3 subunit 7; Eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3, subunit 7 (zeta); eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; RP5-1119A7.12-003; translation initiation factor eIF3 p66; translation initiation factor eIF3 p66 subunit; unnamed protein product
Gene Aliases: 66/67kDa; AA407891; eIF3-p66; eIF3-zeta; EIF3D; eIF3p66; EIF3S7
UniProt ID: (Human) O15371, (Mouse) O70194
Entrez Gene ID: (Human) 8664, (Mouse) 55944
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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