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Product Details
11287-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Hamster,
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EIF3I Fusion Protein Ag1847 (1-325 aa encoded by BC000413)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MKPILLQGH ERSITQIKYN REGDLLFTVA KDPIVNVWYS VNGERLGTYM GHTGAVWCVD ADWDTKHVLT GSADNSCRLW DCETGKQLAL LKTNSAVRTC GFDFGGNIIM FSTDKQMGYQ CFVSFFDLRD PSQIDNNEPY MKIPCNDSKI TSAVWGPLGE CIIAGHESGE LNQYSAKSGE VLVNVKEHSR QINDIQLSRD MTMFVTASKD NTAKLFDSTT LEHQKTFRTE RPVNSAALSP NYDHVVLGGG QEAMDVTTTS TRIGKFEARF FHLAFEEEFG RVKGHFGPIN SVAFHPDGKS YSSGGEDGYV RIHYFDPQYF EFEFEA (1-325 aa encoded by B C000413)
Target Information
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: eIF-3-beta; eIF3 p36; eIF3i; Eukaryotic translation initiation factor 3 subunit 2; Eukaryotic translation initiation factor 3 subunit I; eukaryotic translation initiation factor 3, subunit 1; eukaryotic translation initiation factor 3, subunit 2 (beta); eukaryotic translation initiation factor 3, subunit 2 (beta, 36kD); eukaryotic translation initiation factor 3, subunit 2 beta, 36kDa; eukaryotic translation initiation factor 3, subunit I; predicted protein of HQ2242; subuni; TGF-beta receptor binding protein; TGF-beta receptor-interacting protein 1; TGFbeta receptor-interacting protein 1; TRIP-1
Gene Aliases: 36kDa; D4Ertd632e; eIF3-beta; eIF3-p36; EIF3I; EIF3S2; PRO2242; TRIP-1; TRIP1
UniProt ID: (Human) Q13347, (Mouse) Q9QZD9, (Rat) B0BNA7
Entrez Gene ID: (Human) 8668, (Mouse) 54709, (Rat) 682390
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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