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Proteintech
EXOSC3 Polyclonal Antibody, CoraLite® Plus 488
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Product Details
CL488-15062
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
EXOSC3 fusion protein Ag7065
Conjugate
Excitation/Emission Max
493/522 nm
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
Contains
0.05% ProClin 300
Storage conditions
-20°C, store in dark
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: MAEPASVAA ESLAGSRARA ARTVLGQVVL PGEELLLPEQ EDAEGPGGAV ERPLSLNARA CSRVRVVCGP GLRRCGDRLL VTKCGRLRHK EPGSGSGGGV YWVDSQQKRY VPVKGDHVIG IVTAKSGDIF KVDVGGSEPA SLSYLSFEGA TKRNRPNVQV GDLIYGQFVV ANKDMEPEMV CIDSCGRANG MGVIGQDGLL FKVTLGLIRK LLAPDCEIIQ EVGKLYPLEI VFGMNGRIWV KAKTIQQTLI LANILEACEH MTSDQRKQIF SRLAES
Target Information
EXOSC3 is component of the exosome 3'->5' exoribonuclease complex and is required for the 3' processing of the 7S pre-RNA to the mature 5. 8S rRNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Exosome complex component RRP40; exosome complex exonuclease RRP40; Exosome component 3; hRrp40p; p10; Ribosomal RNA-processing protein 40; RP11-3J10.8
Gene Aliases: 2310005D06Rik; AI593501; bA3J10.7; CGI-102; EXOSC3; hRrp-40; p10; PCH1B; RRP40; Rrp40p
UniProt ID: (Human) Q9NQT5, (Mouse) Q7TQK4
Entrez Gene ID: (Human) 51010, (Rat) 313243, (Mouse) 66362
exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
rRNA processing
nuclear-transcribed mRNA catabolic process, exonucleolytic, 3'-5'
U4 snRNA 3'-end processing
regulation of mRNA stability
exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
DNA deamination
isotype switching
positive regulation of isotype switching
CUT catabolic process
nuclear polyadenylation-dependent rRNA catabolic process
nuclear polyadenylation-dependent tRNA catabolic process
nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription
polyadenylation-dependent snoRNA 3'-end processing
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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