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Invitrogen
FCRL2 Polyclonal Antibody
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FIGURE: 1 / 1
FCRL2 Antibody (PA5-80624) in WB
Western Blot using FCRL2 Polyclonal Antibody (Product # PA5-80624) at 1:500 dilution. Lane A: 293 Whole Cell Lysate. Lysates/proteins at 30 μg per lane. Secondary Goat Anti- RabbitIgG H&L (DyLight™ 800) at 1:10,000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 56 kDa. Observed band size: 64 kDa. (We are unsure of the identity of these extra bands).
Product Details
PA5-80624
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant Human FCRL2/FcRH2 Protein (Met1-Asp395)
Conjugate
Form
Liquid
Concentration
5 mg/mL
Amount
500 µg
Purification
Protein A, Antigen affinity chromatography
Storage buffer
PBS
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human FCRL2/FcRH2.
Target Information
The FCRL2 gene encodes the protein Fc receptor-like 2, which is part of the Fc receptor-like family involved in immune system regulation. FCRL2 is primarily expressed on the surface of B lymphocytes, where it contributes to the modulation of B cell activation and immune responses. As a member of the Fc receptor-like family, FCRL2 is thought to play roles in signaling pathways that influence B cell development, differentiation, and antibody production. It may act as a regulatory receptor that balances immune activation and inhibition, thereby contributing to immune homeostasis and prevention of autoimmunity. The expression of FCRL2 can impact conditions such as autoimmune diseases and B cell-related disorders, where dysregulation of B cell signaling is evident. Research into FCRL2 is ongoing to explore its specific ligand interactions and functional mechanisms, aiming to understand its potential as a therapeutic target for modulating immune responses in diseases characterized by B cell dysfunction.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD307b; Fc receptor homolog 2; Fc receptor-like protein 2; FcR-like protein 2; FcRH2; IFGP family protein 4; Ig-like superfamily receptor; immune receptor translocation-associated protein 4; Immunoglobulin receptor translocation-associated protein 4; immunoglobulin superfamily Fc receptor, gp42; IRTA4; FcRH2; membrane receptor; RP11-367J7.6; SH2 domain containing phosphatase anchor protein 1; SH2 domain-containing phosphatase anchor protein 1; SPAP1a; SPAP1b; SPAP1c; unnamed protein product
Gene Aliases: CD307b; FCRH2; FCRL2; IFGP4; IRTA4; SPAP1; SPAP1A; SPAP1B; SPAP1C; UNQ9236/PRO31998
UniProt ID: (Human) Q96LA5
Entrez Gene ID: (Human) 79368
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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