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Proteintech
FMO5 Polyclonal Antibody
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Product Details
13699-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
FMO5 Fusion Protein Ag4604 (34-285 aa encoded by BC035687)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RTDDIGGLW RFQENPEEGR ASIYKSVIIN TSKEMMCFSD YPIPDHYPNF MHNAQVLEYF RMYAKEFDLL KYIRFKTTVC SVKKQPDFAT SGQWEVVTES EGKKEMNVFD GVMVCTGHHT NAHLPLESFP GIEKFKGQYF HSRDYKNPEG FTGKRVIIIG IGNSGGDLAV EISQTAKQVF LSTRRGAWIL NRVGDYGYPA DVLFSSRLTH FIWKICGQSL ANKYLEKKIN QRFDHEMFGL KPKHRSKDIA LTE (34-285 aa encoded by BC035687)
Target Information
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2 found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenases are NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs, pesticides, and xenobiotics. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Baeyer-Villiger monooxygenase 1; Dimethylaniline monooxygenase [N-oxide-forming] 5; Dimethylaniline oxidase 5; Flavin-containing monooxygenase 5; FMO 5; hBVMO1; Hepatic flavin-containing monooxygenase 5; NADPH oxidase
Gene Aliases: 5033418D19Rik; AI195026; FMO5
UniProt ID: (Human) P49326, (Rat) Q8K4C0, (Mouse) P97872
Entrez Gene ID: (Human) 2330, (Rat) 246248, (Mouse) 14263
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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