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Invitrogen
FMRP Polyclonal Antibody
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Product Details
PA5-117427
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of mouse FMRP. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1.69 mg/mL
Amount
169 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Centrifuge briefly prior to opening.
Target Information
FMR1 binds RNA and is associated with polysomes. The protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure. Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: FMRP; fragile X mental retardation protein 1 homolog; Fragile X messenger ribonucleoprotein; Fragile X messenger ribonucleoprotein 1; mFmr1p; MGC87458; Protein FMR-1
Gene Aliases: Fmr-1; Fmr1; FMRP
UniProt ID: (Mouse) P35922
Entrez Gene ID: (Mouse) 14265
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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