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Invitrogen
FZD9 Polyclonal Antibody
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FIGURE: 1 / 1
FZD9 Antibody (PA5-97000) in WB
Western blot analysis of FZD9 in extracts of various cell lines. Samples were incubated with FZD9 Polyclonal antibody (Product # PA5-97000) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
Product Details
PA5-97000
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 469-591 of human FZD9 (NP_0034991)
Conjugate
Form
Liquid
Concentration
0.64 mg/mL
Amount
64 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ERLNMDFWRL RATEQPCAAA AGPGGRRDCS LPGGSVPTVA VFMLKIFMSL VVGITSGVWV WSSKTFQTWQ SLCYRKIAAG RARAKACRAP GSYGRGTHCH YKAPTVVLHM TKTDPSLENP THL; Positive Samples: TE-1, 293T, HepG2, THP-1, U-251MG, Mouse heart, Mouse brain, Rat skeletal muscle; Cellular Location: Cell membrane, Multi-pass membrane protein
Target Information
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: CD349; CD349 antigen; Frizzled 3; frizzled 9; frizzled 9, seven transmembrane spanning receptor; frizzled family receptor 9; frizzled homolog 9; Frizzled-3; Frizzled-9; Frizzled-like protein 9; Frizzled3; Frizzled9; Fz-9; FzE6; hFz9; mFz3; rFz9; similar to Drosophila frizzled
Gene Aliases: CD349; FZD3; FZD9; mfz9
UniProt ID: (Human) O00144, (Rat) Q8K4C8, (Mouse) Q9R216
Entrez Gene ID: (Human) 8326, (Rat) 266608, (Mouse) 14371
ossification
release of cytochrome c from mitochondria
signal transduction
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
nervous system development
neuroblast proliferation
learning or memory
Wnt signaling pathway
B cell differentiation
positive regulation of bone mineralization
non-canonical Wnt signaling pathway
positive regulation of apoptotic process
negative regulation of neuron apoptotic process
regulation of cytosolic calcium ion concentration
regulation of cell cycle
negative regulation of mitochondrial depolarization
canonical Wnt signaling pathway
negative regulation of necroptotic process
positive regulation of canonical Wnt signaling pathway
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
regulation of skeletal muscle acetylcholine-gated channel clustering
negative regulation of skeletal muscle acetylcholine-gated channel clustering
bone regeneration
positive regulation of neural precursor cell proliferation
multicellular organism development
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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