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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
GIYD2 Fusion Protein Ag13094 (1-275 aa encoded by BC000803) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.39 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MGPAGVAAR PGRFFGVYLL YCLNPRYRGR VYVGFTVNTA RRVQQHNGGR KKGGAWRTSG RGPWEMVLVV HGFPSSVAAL RFEWAWQHPH ASRRLAHVGP RLRGETAFAF HLRVLAHMLR APPWARLPLT LRWVRPDLRQ DLCLPPPPHV PLAFGPPPPQ APAPRRRAGP FDDAEPEPDQ GDPGACCSLC AQTIQDEEGP LCCPHPGCLL RAHVICLAEE FLQEEPGQLL PLEGQCPCCE KSLLWGDLIW LCQMDTEKEV EDSELEEAHW TDLLET (1-275 aa encoded by B C000803)
This gene encodes a protein that is an important regulator of genome stability. The protein represents the catalytic subunit of the SLX1-SLX4 structure-specific endonuclease, which can resolve DNA secondary structures that are formed during repair and recombination processes. Two identical copies of this gene are located on the p arm of chromosome 16 due to a segmental duplication; this record represents the more telomeric copy. Alternative splicing results in multiple transcript variants. Read-through transcription also occurs between this gene and the downstream SULT1A4 (sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4) gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: GIY-YIG domain containing 2; GIY-YIG domain-containing protein 1; SLX1 homolog B; SLX1 structure-specific endonuclease subunit homolog B; SLX1A; SLX1B; Structure-specific endonuclease subunit SLX1
Gene Aliases: 1110030E23Rik; 2410170E21Rik; 4833422P03Rik; AI853643; GIYD1; GIYD2; SLX1; SLX1A; SLX1B
UniProt ID: (Human) Q9BQ83, (Mouse) Q8BX32
Entrez Gene ID: (Human) 79008, (Mouse) 75764
Molecular Function:
endodeoxyribonuclease
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