Recommended positive controls: U87-MG, SK-N-SH, SK-N-AS, HepG2, human LGALS8-transfected 293T, LGALS8 transfected 293T lysate.
Predicted reactivity: Human (99%).
IHC notes, Requires antigen retrieval using heat mediated 10mM Citrate buffer (pH6.0) or Tris-EDTA buffer (pH8.0)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Gal-8; Galectin-8; galectin-8g; lectin, galactoside binding soluble 8; lectin, galactoside-binding, soluble, 8; PCTA-1; Po66 carbohydrate binding protein; Po66 carbohydrate-binding protein; Po66-CBP; Prostate carcinoma tumor antigen 1; RP11-385F5.1
Gene Aliases: Gal-8; LGALS8; PCTA-1; PCTA1; Po66-CBP
UniProt ID: (Human) O00214
Entrez Gene ID: (Human) 3964