This target displays homology in the following species: Human: 100%; Yeast: 77%
DNA-binding protein that seems to act as a transcription factor (PubMed:19584537). Involved in the regulation of neuronal differentiation, acts upon JNK-signaling pathway activation and plays a role in neurite outgrowth in hippocampal cells. May mediate with FIBP FGF-signaling in the establishment of laterality in the embryo. Promotes cell motility, seems to stimulate tumor metastasis (PubMed:22120713).
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Protein Aliases: chxI protein homolog; ETR101; IER2; Immediate early response gene 2 protein; PIP92; Protein ETR101
Gene Aliases: ETR101; IER2; PIP92
UniProt ID: (Human) Q9BTL4
Entrez Gene ID: (Human) 9592