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IKAP Polyclonal Antibody
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FIGURE: 1 / 3
IKAP Antibody (PA5-29112) in ICC/IF
IKAP Polyclonal Antibody detects IKAP protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in ice-cold MeOH for 5 min. Green: IKAP protein stained by IKBKAP antibody [C1C2], Internal (Product # PA5-29112) diluted at 1:500. Blue: Hoechst 33343 staining.
Product Details
PA5-29112
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human IKAP. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.01% thimerosal
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: HeLa, HepG2, GL261, Raw264.7.
Predicted reactivity: Mouse (86%), Rat (85%), Rabbit (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
The protein encoded by this gene is a scaffold protein and a regulator for 3 different kinases involved in proinflammatory signaling. This encoded protein can bind NF-kappa-B-inducing kinase (NIK) and IKKs through separate domains and assemble them into an active kinase complex. Mutations in this gene have been associated with familial dysautonomia.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp781H1425; Elongator complex protein 1; ELP1; FLJ12497; IkappaB kinase complex-associated protein; IKK complex-associated protein; IKK-complex-associated protein IKAP; inhibitor of kappa light polypeptide enhancer in B-cells, kinase complex-associated protein; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein; p150; RP11-3J11.4; unnamed protein product
Gene Aliases: 3110040G09Rik; 6030413P05; C78473; DYS; ELP1; FD; IKAP; IKBKAP; IKI3; TOT1
UniProt ID: (Human) O95163, (Mouse) Q7TT37
Entrez Gene ID: (Human) 8518, (Mouse) 230233
tRNA wobble uridine modification
tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation
regulation of translation
tRNA processing
transcription, DNA-templated
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
I-kappaB phosphorylation
positive regulation of cell migration
regulation of protein kinase activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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