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Proteintech
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Immunogen sequence: MDVLASYSI FQELQLVHDT GYFSALPSLE ETWQQTCLEL ERYLQTEPRR ISETFGEDLD CFLHASPPPC IEESFRRLDP LLLPVEAAIC EKSSAVDILL SRDKLLSETC LSLQPASSSL DSYTAVNQAQ LNAVTSLTPP SSPELSRHLV KTSQTLSAVD GTVTLKLVAK KAALSSVKVR SLISAHGRDV SGVLHEAMSS RGTTGNTQVQ SPSNATTATG VFPGLTILPS T (1-230 aa encoded by BC012919)
The protein encoded by this gene is a member of the Kruppel-like transcriptional regulator family. Members in this family regulate cell proliferation, differentiation and survival and contain three C2H2 zinc fingers at the C-terminus that mediate binding to GC-rich sites. This protein may contribute to the progression of type 2 diabetes by inhibiting insulin expression and secretion in pancreatic beta-cells and by deregulating adipocytokine secretion in adipocytes. A pseudogene of this gene is located on the long arm of chromosome 3. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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