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Invitrogen
ITGA8 Monoclonal Antibody (481709)
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FIGURE: 1 / 2
ITGA8 Antibody (MA5-24196) in ICC/IF
Immunocytochemistry analysis of ITGA8 in immersion fixed H4 human neuroglioma cell line. Samples were incubated in ITGA8 monoclonal antibody (Product # MA5-24196) using a dilution of 10 µg/mL for 3 hours at room temperature followed by NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red) and counterstained with DAPI (blue). Specific staining was localized to cell surfaces and cytoplasm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-24196
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b
Class
Monoclonal
Type
Antibody
Clone
481709
Immunogen
E. coli-derived recombinant human Integrin alpha 8 Glu610-Leu800
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Lyophilized
Concentration
0.5 mg/mL
Amount
100 µg
Purification
Protein A/G
Storage buffer
PBS with 5% trehalose
Contains
No Preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute in sterile PBS to a final concentration of 0.5 mg/mL.
Target Information
Integrin alpha-8/beta-1 functions in the genesis of kidney and probably of other organs by regulating the recruitment of mesenchymal cells into epithelial structures. It recognizes the sequence R-G-D in a wide array of ligands including TNC, FN1, SPP1 TGF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: integrin, alpha 8; unnamed protein product
UniProt ID: (Human) P53708
Entrez Gene ID: (Human) 8516
formation of primary germ layer
kidney development
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
tissue development
cell differentiation
cell-substrate adhesion
substrate adhesion-dependent cell spreading
establishment of protein localization
positive regulation of transcription from RNA polymerase II promoter
mesodermal cell differentiation
smooth muscle tissue development
smooth muscle cell differentiation
cell-cell adhesion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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