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Invitrogen
S100A7 Recombinant Rabbit Monoclonal Antibody (128)
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FIGURE: 1 / 2
S100A7 Antibody (MA5-43136) in ICC/IF
Immunocytochemistry analysis of S100A7 in HeLa cells. Samples were treated with 4% PFA, permeabilized with 1% Triton X-100 in PBS, and blocked with 10% serum, incubated in S100A7 monoclonal antibody (Product # MA5-43136) at a dilution of 1:60, followed by Alexa Fluor 594-conjugated Goat Anti-rabbit IgG.
Product Details
MA5-43136
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293 cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
128
Immunogen
Recombinant Human S100A7 protein.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
PBS
Contains
no preservative
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Specificity: Human S100A7
Target Information
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein S100-A7; Psoriasin; psoriasin 1; S100 calcium-binding protein A7; S100A7
Gene Aliases: PSOR1; S100A7; S100A7C
UniProt ID: (Human) P31151
Entrez Gene ID: (Human) 6278
response to reactive oxygen species
angiogenesis
epidermis development
positive regulation of T cell chemotaxis
keratinocyte differentiation
response to lipopolysaccharide
endothelial cell migration
antimicrobial humoral immune response mediated by antimicrobial peptide
positive regulation of ERK1 and ERK2 cascade
positive regulation of granulocyte chemotaxis
positive regulation of monocyte chemotaxis
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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