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Product Details
PA5-103817
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human MARCH9(Accession Q86YJ5), corresponding to amino acid residues C46-S96.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
RRID
AB_2853150
Product Specific Information
Antibody detects endogenous levels of total MARCH9.
Target Information
MARCH9 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH9 induces internalization of several membrane glycoproteins and directs them to the endosomal compartment.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 9-Mar; E3 ubiquitin-protein ligase MARCH9; E3 ubiquitin-protein ligase MARCHF9; MARCH-IX; membrane associated ring finger 9; membrane-associated ring finger (C3HC4) 9; Membrane-associated RING finger protein 9; Membrane-associated RING-CH protein IX; RING finger protein 179; RING-type E3 ubiquitin transferase MARCHF9
Gene Aliases: AI608492; BC019560; MARCH-IX; MARCH9; MARCHF9; RNF179
UniProt ID: (Human) Q86YJ5, (Mouse) Q3TZ87
Entrez Gene ID: (Human) 92979, (Mouse) 216438
zinc ion binding
ligase activity
molecular_function
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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