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Invitrogen
MAST4 Polyclonal Antibody
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FIGURE: 1 / 3
MAST4 Antibody (PA5-36976) in IHC (P)
Immunohistochemistry analysis of MAST4 in paraffin-embedded human rectum carcinoma tissue (cytoplasmic staining) and negative control (right, with PBS only). Samples were incubated with MAST4 polyclonal antibody (Product # PA5-36976) at a dilution of 1:50, followed by goat Anti-Rabbit IgG-biotin and avidin peroxidase.
Product Details
PA5-36976
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to amino acids 108-153 of human MAST4
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
This antibody detects endogenous protein at a molecular weight of 266 kDa.
Purity is >95% by SDS-PAGE.
Target Information
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine(Ser/Thr) protein kinases. MAST4 (microtubule associated serine/threonine kinase family member 4), also known as KIAA0303, is a 2,626 amino acid protein that localizes to the cytoplasm and contains one protein kinase domain, as well as one PDZ domain and one AGC-kinase C-terminal domain. Expressed at high levels in most adult tissues, including testis, colon and small intestine, MAST4 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Multiple isoforms of MAST4 exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: mast4; microtubule associated serine/threonine kinase family member 4; Microtubule-associated serine/threonine-protein kinase 4
Gene Aliases: 4930420O11Rik; AI642422; KIAA0303; MAST4; mKIAA0303; RGD1310139
UniProt ID: (Human) O15021, (Mouse) Q811L6
Entrez Gene ID: (Human) 375449, (Mouse) 328329, (Rat) 100912235
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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