Immunogen sequence: IFYTLGECGL ISFSDYIFLT TVLSTPQRNF EIAFKMFDLN GDGEVDMEEF EQVQSIIRSQ TSMGMRHRDR PTTGNTLKSG LCSALTTY
MICU1 is a key regulator of mitochondrial calcium uptake required for calcium entry into mitochondrion. It may act as a calcium sensor via its EF-hand domains, gating the activity of a calcium channel partner. MICU1 induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: ara CALC; Atopy-related autoantigen CALC; CALC; Calcium uptake protein 1, mitochondrial; Calcium-binding atopy-related autoantigen 1; CBARA1; EFHA3; FLJ12684; Hom s 4
Gene Aliases: CALC; CBARA1; EFHA3; MICU1; MPXPS
UniProt ID: (Human) Q9BPX6
Entrez Gene ID: (Human) 10367