This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
A suggested positive control is Jurkat cell lysate.
PA5-19919 can be used with blocking peptide PEP-0045.
The PA5-19919 immunogen is located within the last 50 amino acids of MYD88.
Predicted molecular ~ 35kD. In Western blot applications, this antibody has been observed to detect a band at: 35kD
Predicted species reactivity based on immunogen sequence: Pig: (94%), Sheep: (82%), Bovine: (82%), Chicken: (82%)
Myeloid differentiation Marker 88 (MyD88) is an adaptor molecule for the Toll/IL-1R and is involved in the inflammatory response induced by IL-1, IL-18 and LPS. MyD88 recruits IRAK to IL-1 receptor complex in response to IL-1. This pathway further leads to activation of NF-kB. MyD88 has a wide tissue distribution.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: mutant myeloid differentiation primary response 88; myeloid differentiation primary response gene (88); myeloid differentiation primary response gene 88; Myeloid differentiation primary response protein MyD88
Gene Aliases: MYD88; MYD88D