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This gene encodes a member of the oxysterol-binding protein family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms.
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Protein Aliases: DCDC4A; FLJ10217; FLJ50293; FLJ55454; FLJ79410; ORP-1; OSBP-related protein 1; oxysterol binding protein-like 1A; oxysterol binding protein-like 1B; Oxysterol-binding protein-related protein 1; oxysterol-binding protein-related protein 1 variant 1; oxysterol-binding protein-related protein 1 variant 2
Gene Aliases: G430090F17Rik; Gm753; ORP-1; ORP1; Orp1a; Orp1l; OSBP8; OSBPL1; OSBPL1A; OSBPL1B
UniProt ID: (Human) Q9BXW6, (Rat) Q8K4M9, (Mouse) O88318
Entrez Gene ID: (Human) 114876, (Rat) 259221, (Mouse) 64291
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