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Invitrogen
TAF9 Polyclonal Antibody
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Product Details
PA5-40919
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human TAF9
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: GLKYINVGDL AREEQLYDGY DEEYDCPILD EDRVVDELDN QMREGGVIVD
Sequence homology: Cow: 93%; Guinea Pig: 79%; Horse: 86%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 79%; Rat: 90%
Target Information
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds to the basal transcription factor GTF2B as well as to several transcriptional activators such as p53 and VP16. A similar but distinct gene (TAF9L) has been found on the X chromosome and a pseudogene has been identified on chromosome 19. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AD-004; CGI-137; CIP; hCINAP; MGC:1603; MGC:3647; RNA polymerase II TBP-associated factor subunit G; STAF31/32; TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa; TAFII-31; TAFII-32; TATA box binding protein associated factor 9; transcription initiation factor TFIID 31 kD subunit; Transcription initiation factor TFIID 31 kDa subunit; Transcription initiation factor TFIID 32 kDa subunit; Transcription initiation factor TFIID subunit 9
Gene Aliases: MGC:5067; STAF31/32; TAF2G; TAF9; TAFII-31; TAFII-32; TAFII31; TAFII32; TAFIID32
UniProt ID: (Human) Q16594
Entrez Gene ID: (Human) 6880
p53 binding
DNA binding
transcription coactivator activity
histone acetyltransferase activity
protein binding
activating transcription factor binding
transcription regulatory region DNA binding
protein heterodimerization activity
ATPase binding
C2H2 zinc finger domain binding
chromatin/chromatin-binding, or -regulatory protein
box C/D snoRNP assembly
transcription from RNA polymerase II promoter
transcription initiation from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
cellular response to DNA damage stimulus
positive regulation of cell growth
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
snRNA transcription from RNA polymerase II promoter
negative regulation of apoptotic process
histone H3 acetylation
positive regulation of transcription from RNA polymerase II promoter
protein stabilization
positive regulation of response to cytokine stimulus
response to interleukin-1
regulation of signal transduction by p53 class mediator
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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