|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||C-terminal cyclic peptide unique to all PDE4D subtypes variants.|
|Purification||Antigen affinity chromatography|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-31136 detects PDE4D from mouse, human, rat samples.
PA1-31136 has been successfully used in immunocytochemistry, immunoprecipitation, Western blot applications.
The PA1-31136 immunogen is: C-terminal cyclic peptide unique to all PDE4D subtypes variants.
This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. The encoded protein has 3',5'-cyclic-AMP phosphodiesterase activity and degrades cAMP, which acts as a signal transduction molecule in multiple cell types. This gene uses different promoters to generate multiple alternatively spliced transcript variants that encode functional proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.