This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: SVTEPKLATP AGLKKSSKKA EPVKVLQKEK KRGKRVALSD DETKETENMR KKRRRIKLPE SDSSEDEVFP DSPGAY
Highest antigen sequence identity to the following orthologs: Mouse - 75%, Rat - 75%.
DNA replication, recombination and repair, all of which are necessary for genomic stability, require the presence of exonucleases. In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol alpha, beta, delta and epsilon. DNA pol delta and DNA pol epsilon are multisubunit enzymes, with DNA pol delta consisting of two subunits which interact with the sliding DNA clamp protein PCNA. DNA pol delta 3, also known as POLD3 or p66, is a 466 amino acid nuclear protein that is required for the proper function of DNA pol delta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: DNA pol delta p66; DNA pol delta3; DNA polymerase delta subunit 3; DNA polymerase delta subunit C; DNA polymerase delta subunit p66; DNA polymerase delta subunit p68; DNApol delta3; KIAA0039; Pol delta C subunit (p66); POLD3; polymerase (DNA) delta 3, accessory subunit; polymerase (DNA-directed), delta 3, accessory subunit; protein phosphatase 1, regulatory subunit 128
Gene Aliases: KIAA0039; P66; P68; POLD3; PPP1R128
UniProt ID: (Human) Q15054
Entrez Gene ID: (Human) 10714