The protein encoded by this gene contains 2 leucine zipper domains and a putative C-terminal nuclear targeting signal, but does not have any hydrophobic regions. This protein is expressed weakly in resting NK and T cells. The encoded protein modulates the activation of ARF genes by CYTH1. This protein interacts with CYTH1 and SNX27 proteins and may act to sequester CYTH1 protein in the cytoplasm.
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Protein Aliases: CASP; Cbp HE; CYBR; Cytohesin binder and regulator; cytohesin binding protein; cytohesin binding protein HE; cytohesin-1 interacting protein; Cytohesin-associated scaffolding protein; Cytohesin-binding protein HE; Cytohesin-interacting protein; Pleckstrin homology Sec7 and coiled-coil domain-binding protein; Pleckstrin homology Sec7 and coiled-coil domains-binding protein; pleckstrin homology, Sec7 and coiled-coil domains, binding protein; pleckstrin homology, Sec7 and coiled/coil domains, binding protein; Sec7; tamalin
Gene Aliases: A130053M09Rik; AI462064; B3-1; C80816; CASP; Cbp; CYBR; CYTHIP; CYTIP; HE; PSCDBP