Proteintech

RAB14 Polyclonal Antibody

Tech Support

Datasheet

Protocols

Questions & Answers

Tech Support

Product Image Gallery

RAB14 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human ovary tumor tissue slide using 15662-1-AP (RAB14 antibody) at dilution of 1:200 (under 40x lens) heat mediated antigen retrieved with Tris-EDTA buffer (pH 9).

RAB14 Antibody in Western Blot (WB) — Human kidney tissue were subjected to SDS PAGE followed by western blot with 15662-1-AP (RAB14 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

Product Details

15662-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2400	View 4 publications 4 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:50-1:500	-
Immunohistochemistry (IHC)	-	View 3 publications 3 publications
Miscellaneous PubMed (Misc)	-	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	RAB14 Fusion Protein Ag8092 (1-215 aa encoded by BC006081) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.27 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MATAPYNYS YIFKYIIIGD MGVGKSCLLH QFTEKKFMAD CPHTIGVEFG TRIIEVSGQK IKLQIWDTAG QERFRAVTRS YYRGAAGALM VYDITRRSTY NHLSSWLTDA RNLTNPNTVI ILIGNKADLE AQRDVTYEEA KQFAEENGLL FLEASAKTGE NVEDAFLEAA KKIYQNIQDG SLDLNAAESG VQHKPSAPQG GRLTSEPQPQ REGCGC (1-215 aa encoded by B C006081)

Target Information

Localized to biosynthetic and endosomal compartments, Rab14 is involved in the biosynthetic/recycling pathway between the Golgi and endosomal compartments.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Rab14 overexpression regulates gemcitabine sensitivity through regulation of Bcl-2 and mitochondrial function in pancreatic cancer.

Virchows Archiv : an international journal of pathology

Ge J,Ge C

Tue Jan 01 00:00:00 EST 2019

Rab14 overexpression regulates gemcitabine sensitivity through regulation of Bcl-2 and mitochondrial function in pancreatic cancer.

Virchows Archiv : an international journal of pathology

Ge J,Ge C

Tue Jan 01 00:00:00 EST 2019

Hypermethylation of miR-338-3p and Impact of its Suppression on Cell Metastasis Through N-Cadherin Accumulation at the Cell -Cell Junction and Degradation of MMP in Gastric Cancer.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Guo B,Zhang J,Li Q,Zhao Z,Wang W,Zhou K,Wang X,Tong D,Zhao L,Yang J,Huang C

Fri Nov 02 00:00:00 EDT 2018

Hypermethylation of miR-338-3p and Impact of its Suppression on Cell Metastasis Through N-Cadherin Accumulation at the Cell -Cell Junction and Degradation of MMP in Gastric Cancer.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology

Guo B,Zhang J,Li Q,Zhao Z,Wang W,Zhou K,Wang X,Tong D,Zhao L,Yang J,Huang C

Fri Nov 02 00:00:00 EDT 2018

Rab14 Act as Oncogene and Induce Proliferation of Gastric Cancer Cells via AKT Signaling Pathway.

PloS one

Guo B,Wang W,Zhao Z,Li Q,Zhou K,Zhao L,Wang L,Yang J,Huang C

Wed Aug 23 00:00:00 EDT 2017

Rab14 is overexpressed in ovarian cancers and promotes ovarian cancer proliferation through Wnt pathway.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Hou R,Jiang L,Yang Z,Wang S,Liu Q

Fri Oct 07 00:00:00 EDT 2016

Rab14 is overexpressed in ovarian cancers and promotes ovarian cancer proliferation through Wnt pathway.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Hou R,Jiang L,Yang Z,Wang S,Liu Q

Fri Oct 07 00:00:00 EDT 2016

MiR-451 increases radiosensitivity of nasopharyngeal carcinoma cells by targeting ras-related protein 14 (RAB14).

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine

Zhang T,Sun Q,Liu T,Chen J,Du S,Ren C,Liao G,Yuan Y

Mon Dec 01 00:00:00 EST 2014

Bioinformatics

Protein Aliases: bA165P4.3 (member RAS oncogene family); F protein-binding protein 1; GTPase Rab14; Ras-related protein Rab-14; small GTP binding protein RAB14

Gene Aliases: 0610030G24Rik; 2810475J17Rik; A830021G03Rik; AI314285; AI649155; D030017L14Rik; FBP; RAB-14; RAB14

UniProt ID: (Human) P61106, (Mouse) Q91V41, (Rat) P61107

Entrez Gene ID: (Human) 51552, (Mouse) 68365, (Rat) 94197

Function(s)

transport intracellular protein transport Golgi to endosome transport small GTPase mediated signal transduction body fluid secretion metabolic process fibroblast growth factor receptor signaling pathway embryo development protein transport endocytic recycling Rab protein signal transduction regulation of protein localization apical protein localization phagolysosome assembly involved in apoptotic cell clearance vesicle-mediated transport intracellular transport defense response to bacterium membrane organization

Process(es)

glycoprotein binding GTPase activity protein binding GTP binding GDP binding myosin V binding nucleotide binding

RAB14 Polyclonal Antibody

Product Details

15662-1-AP

Western Blot (WB)

Immunohistochemistry (Paraffin) (IHC (P))

Immunohistochemistry (IHC)

Miscellaneous PubMed (Misc)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!