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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: EYKLLHEYW MALRNRVSAV DELAMATERL RVRDPREPKP NPPVLHIIEP HEVEQNRIKL LNDKAFATSQ LQKKLGQLLY LTNLEKSQDK TSGGVNPEPC PICARQLGKQ WAVLTCGHCF CNECISIIIE QYSVGSHRSS IKCAICRQTT SHKEISYVFT SEKANQEEDI PVKGSHSTKV EAVVRTLMKI QLRDPGAKAL VFSTWQDVLD IISKALTDNN MEFAQISRVK TFQENLSAFK RDPQINILLL PLHTGSNGLT IIEATHVLLV EPILNPAHEL QAIGRVHRIG QTKPTIVHRF LIKATIEERM QAMLKTAERS HTNSSAKHSE ASVLTVADLA DLFTKETEEL E (1334-1683 aa encoded by BC117686)
A novel gene containing SNF2, PHD-finger, RING-finger, helicase, and linker histone domains termed SHPRH, is a possible candidate for a tumor suppressor gene. These domains are characteristic of several DNA repair proteins, transcription factors, and helicases. Mapping of this gene to 6q24, a region reported to contain a tumor suppressor locus suggests a role in tumor suppression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2610103K11Rik; RING-type E3 ubiquitin transferase SHPRH; SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase; SNF2, histone-linker, PHD and RING finger domain-containing helicase; unnamed protein product
Gene Aliases: 2610103K11Rik; bA545I5.2; D230017O13Rik; E130018M05; RAD5
UniProt ID: (Human) Q149N8, (Mouse) Q7TPQ3
Entrez Gene ID: (Human) 257218, (Mouse) 268281
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