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Invitrogen

SUCLG2 Polyclonal Antibody

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SUCLG2 Polyclonal Antibody

Product Details

PA5-97170

Applications
Tested Dilution
Publications

Western Blot (WB)

1:1,000-1:5,000
-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200
-

Immunocytochemistry (ICC/IF)

1:50-1:100
-

ELISA (ELISA)

1 µg/mL
-
Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 50-300 of human SUCLG2 (NP_0038392)
3D Epitope / Immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.56 mg/mL

Amount

156 µg

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.01% thimerosal

Storage conditions

-20°C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2808972

Product Specific Information

Immunogen sequence: SDNGVRVQRF FVADTANEAL EAAKRLNAKE IVLKAQILAG GRGKGVFNSG LKGGVHLTKD PNVVGQLAKQ MIGYNLATKQ TPKEGVKVNK VMVAEALDIS RETYLAILMD RSCNGPVLVG SPQGGVDIEE VAASNPELIF KEQIDIFEGI KDSQAQRMAE NLGFVGPLKS QAADQITKLY NLFLKIDATQ VEVNPFGETP EGQVVCFDAK INFDDNAEFR QKDIFAMDDK SENEPIENEA AKYDLKYIGL D; Positive Samples: HT-29, 293T, LO2, U-87MG, MCF7, Raji, Mouse spleen, Rat spleen; Cellular Location: Mitochondrion

Target Information

This gene encodes a GTP-specific beta subunit of succinyl-CoA synthetase. Succinyl-CoA synthetase catalyzes the reversible reaction involving the formation of succinyl-CoA and succinate. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 5 and 12.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: G-BETA; G-SCS; GTP-specific succinyl-CoA synthetase beta subunit; GTP-specific succinyl-CoA synthetase subunit beta; Itaconyl--CoA ligase [GDP-forming] subunit beta; Malyl--CoA ligase [GDP-forming] subunit beta; SCS-betaG; Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; succinate-CoA ligase GDP-forming beta subunit; succinate-Coenzyme A ligase, GDP-forming, beta subunit; succinyl-CoA ligase [GDP-forming] subunit beta, mitochondrial; succinyl-CoA ligase, GDP-forming, beta chain, mitochondrial; Succinyl-CoA synthetase beta-G chain; succinyl-CoA synthetase, beta-G chain; unnamed protein product

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Gene Aliases: AF171077; AW556404; D6Wsu120e; G-SCS; GBETA; GTPSCS; SCS-betaG; SUCLG2

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UniProt ID: (Human) Q96I99, (Mouse) Q9Z2I8

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Entrez Gene ID: (Human) 8801, (Mouse) 20917, (Rat) 362404

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Function(s)
nucleotide binding magnesium ion binding catalytic activity succinate-CoA ligase (ADP-forming) activity succinate-CoA ligase (GDP-forming) activity protein binding ATP binding GTP binding ligase activity GDP binding macromolecular complex binding metal ion binding acyl-CoA ligase activity succinate-CoA ligase activity succinate-semialdehyde dehydrogenase (NAD+) activity 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity fatty acid ligase activity 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity benzoyl acetate-CoA ligase activity 2,4-dichlorobenzoate-CoA ligase activity pivalate-CoA ligase activity cyclopropanecarboxylate-CoA ligase activity adipate-CoA ligase activity citronellyl-CoA ligase activity mentha-1,3-dione-CoA ligase activity thiophene-2-carboxylate-CoA ligase activity 2,4,4-trimethylpentanoate-CoA ligase activity cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity branched-chain acyl-CoA synthetase (ADP-forming) activity aryl-CoA synthetase (ADP-forming) activity 3-hydroxypropionyl-CoA synthetase activity protein heterodimerization activity perillic acid:CoA ligase (ADP-forming) activity perillic acid:CoA ligase (AMP-forming) activity (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity pristanate-CoA ligase activity malonyl-CoA synthetase activity ligase
Process(es)
tricarboxylic acid cycle succinyl-CoA metabolic process succinate metabolic process succinyl-CoA catabolic process metabolic process oxidation-reduction process
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