This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Knockout studies in mice indicate that this gene is important for specification of paraxial mesoderm structures.
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Protein Aliases: rib-vertebrae; T-box protein 6; T-box transcription factor TBX6
Gene Aliases: rv; SCDO5; TBX6
Molecular Function: Rel homology transcription factor