This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: KVRASGDAKI KKEKENGFSS PPQIKDEPED DGYFVPPKED IKPLKRPRDE DDADYKPKK
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22.
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Protein Aliases: DNA topoisomerase 1; DNA topoisomerase I; RP3-511B24.2; type I DNA topoisomerase
Gene Aliases: Ab2-086; AI467334; D130064I21Rik; Top-1; TOP1; TOPI
Molecular Function: DNA topoisomerase