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Product Details
PA5-67941
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthesized peptide derived from human TRAM2.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
AB_2691786
Product Specific Information
Predicted to react with Mouse and Rat samples.
Target Information
Necessary for collagen type I synthesis. May couple the activity of the ER Ca(2+) pump SERCA2B with the activity of the translocon. This coupling may increase the local Ca(2+) concentration at the site of collagen synthesis, and a high Ca(2+) concentration may be necessary for the function of molecular chaperones involved in collagen folding. Required for proper insertion of the first transmembrane helix N-terminus of TM4SF20 into the ER lumen, may act as a ceramide sensor for regulated alternative translocation (RAT).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: TRAM-like protein; Translocating chain-associated membrane protein 2; translocating chain-associating membrane protein 2
Gene Aliases: C330003D03Rik; KIAA0057; TRAM2
UniProt ID: (Human) Q15035, (Mouse) Q924Z5
Entrez Gene ID: (Rat) 100361830, (Human) 9697, (Mouse) 170829
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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