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Invitrogen
TTLL12 Polyclonal Antibody
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Product Details
PA5-117122
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-450 of human TTLL12 (NP_0559551)
Conjugate
Form
Liquid
Concentration
1.84 mg/mL
Amount
184 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Samples: HeLa, Jurkat, HL-60, Mouse brain, Mouse spinal cord, Mouse heart, Rat brain
Immunogen sequence: MEAERGPERR PAERSSPGQT PEEGAQALAE FAALHGPALR ASGVPERYWG RLLHKLEHEV FDAGEVFGIM QVEEVEEEED EAAREVRKQQ PNPGNELCYK VIVTRESGLQ AAHPNSIFLI DHAWTCRVEH ARQQLQQVPG LLHRMANLMG IEFHGELPST EAVALVLEEM WKFNQTYQLA HGTAEEKMPV WYIMDEFGSR IQHADVPSFA TAPFFYMPQQ VAYTLLWPLR DLDTGEEVTR DFAYGETDPL IRKCMLLPWA PTDMLDLSSC TPEPPAEHYQ AILEENKEKL PLDINPVVHP HGHIFKVYTD VQQVASSLTH PRFTLTQSEA DADILFNFSH FKDYRKLSQE RPGVLLNQFP CENLLTVKDC LASIARRAGG PEGPPWLPRT FNLRTELPQF VSYFQQRERW GEDNHWICKP WNLARSLDTH VTKSLHSIIR HRESTPKVVS
Target Information
TTLL12 (tubulin tyrosine ligase-like family, member 12) is a 644 amino acid protein that contains one TTL domain. Of the fourteen members of the TTLL family that modify tubulin, TTLL12 is the least characterized member. TTLL12 is highly expressed in a multitude of metastatic prostate cancer cell lines, therefore, it is considered a target for tumor therapy. Overexpression of TTLL12 is suggested to alter chromosome ploidy, whereas downregulation of TTLL12 influence several post-translational modifications of tubulin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: dJ526I14.2; Inactive tubulin--tyrosine ligase-like protein 12; KIAA0153; TTL domain protein; ttll12; tubulin tyrosine ligase-like family, member 12; Tubulin--tyrosine ligase-like protein 12; unnamed protein product
Gene Aliases: BC055368; D430005B17; dJ526I14.2; KIAA0153; RGD1305319; TTLL12
UniProt ID: (Human) Q14166, (Mouse) Q3UDE2
Entrez Gene ID: (Human) 23170, (Rat) 300105, (Mouse) 223723
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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