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Proteintech
UBE4A Polyclonal Antibody
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Product Details
21548-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
UBE4A Fusion Protein Ag16211 (717-1066 aa encoded by BC112367)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Amount
31.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: QLAEALIKV FVDIEFTGDP HQFEQKFNYR RPMYPILRYM WGTDTYRESI KDLADYASKN LEAMNPPLFL RFLNLLMNDA IFLLDEAIQY LSKIKIQQIE KDRGEWDSLT PEARREKEAG LQMFGQLARF HNIMSNETIG TLAFLTSEIK SLFVHPFLAE RIISMLNYFL QHLVGPKMGA LKVKDFSEFD FKPQQLVSDI CTIYLNLGDE ENFCATVPKD GRSYSPTLFA QTVRVLKKIN KPGNMIMAFS NLAERIKSLA DLQQQEEETY ADACDEFLDP IMSTLMCDPV VLPSSRVTVD RSTIARHLLS DQTDPFNRSP LTMDQIRPNT ELKEKIQRWL AERKQQKEQL E (717-1066 aa encoded by BC112367)
Target Information
Ubiquitination requires a ubiquitin-activating enzyme, a ubiquitin-conjugating enzyme, and usually a substrate-specific ubiquitin-protein ligase. Multiubiquitination needs a fourth factor, to bind to the ubiquitin moieties of preformed conjugates and catalyze ubiquitin chain assembly in conjunction with the first three proteins. Human protein KIAA0126, with a predicted 1,073 amino acid residues, is a member of the novel protein family defined by ubiquitination conjugation factor E4. In yeast, E4 activity is linked to cell survival under stress conditions, indicating that eucaryotes use E4-dependent proteolysis pathways for multiple cellular functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: KIAA0126; RING-type E3 ubiquitin transferase E4 A; Ubiquitin conjugation factor E4 A; ubiquitination factor E4A (UFD2 homolog, yeast); ubiquitination factor E4A, UFD2 homolog; unnamed protein product
Gene Aliases: 4732444G18Rik; 9930123J21Rik; E4; KIAA0126; NEDHMS; UBE4A; UBOX2; UFD2; UFD2b
UniProt ID: (Human) Q14139, (Mouse) E9Q735
Entrez Gene ID: (Human) 9354, (Mouse) 140630
ubiquitin-protein transferase activity
protein binding
transferase activity
ubiquitin-ubiquitin ligase activity
ubiquitin protein ligase activity
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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