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Invitrogen
UGT1A7 Polyclonal Antibody
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Product Details
PA5-43352
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human UGT1A7 (aa 74-123).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: VKTYSTSYTL EDQDREFMVF ADARWTAPLR SAFSLLTSSS NGIFDLFFSN
Sequence homology: Human: 100%
Target Information
UGT1A7 is an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene has moderate glucuronidase activity with phenols.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Bilirubin-specific UDPGT isozyme 1; UDP glucuronosyltransferase 1 family, polypeptide A7; UDP glycosyltransferase 1 family, polypeptide A7; UDP-glucuronosyltransferase 1 family polypeptide A7s; UDP-glucuronosyltransferase 1-1; UDP-glucuronosyltransferase 1-7; UDP-glucuronosyltransferase 1-A; UDP-glucuronosyltransferase 1-G; UDP-glucuronosyltransferase 1A1; UDP-glucuronosyltransferase 1A7; UDPGT 1-7; UGT-1G; UGT1A7
Gene Aliases: GNT1; hUG-BR1; UDPGT; UDPGT 1-7; UGT-1A; UGT-1G; UGT1; UGT1-01; UGT1-07; UGT1.1; UGT1.7; UGT1A; UGT1A1; UGT1A7; UGT1G
UniProt ID: (Human) Q9HAW7
Entrez Gene ID: (Human) 54577
retinoic acid binding
enzyme inhibitor activity
protein kinase C binding
protein binding
UDP-glycosyltransferase activity
glucuronosyltransferase activity
transferase activity
transferase activity, transferring glycosyl groups
enzyme binding
protein homodimerization activity
protein heterodimerization activity
liver development
lipid metabolic process
fatty acid metabolic process
xenobiotic metabolic process
estrogen metabolic process
toxin catabolic process
coumarin metabolic process
flavonoid metabolic process
xenobiotic catabolic process
retinoic acid metabolic process
negative regulation of fatty acid metabolic process
flavone metabolic process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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