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Proteintech
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Immunogen sequence: KVLVWAAEY SHWMNIKTIL DELIQRGHEV TVLASSASIL FDPNNSSALK IEIYPTSLTK TELENFIMQQ IKRWSDLPKD TFWLYFSQVQ EIMSIFGDIT RKFCKDVVSN KKFMKKVQES RFDVIFADAI FPCSELLAEL FNIPFVYSLS FSPGYTFEKH SGGFIFPPSY VPVVMSELTD QMTFMERVKN MIYVLYFDFW FEIFDMKKWD QFYSEVLGRP TTLSETMGKA DVWLIRNSWN FQFPYPLLPN VDFVGGLHCK PAKPLPKEME DFVQSSGENG VVVFSLGSMV SNMTEERANV IASALAQIPQ KVLWRFDGNK PDTLGLNT (25-351 aa encoded by BC030974 )
The UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 3,4-catechol estrogen specific; 3,4-catechol estrogen-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B7; UDP-glucuronosyltransferase (EC 2.4.1.17); UDP-glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B8; UDP-glucuronosyltransferase 2B9; UDP-glucuronosyltransferase isoform; UDP-glucuronyltransferase, family 2, beta-7; UDPGT; UDPGT 2B7; UDPGT 2B8; UDPGT 2B9; UDPGTh 2; UDPGTh-2; UGT2B-RH4; unnamed protein product
Gene Aliases: UDPGT 2B7; UDPGT 2B9; UDPGT2B7; UDPGTh-2; UDPGTH2; UGT2B7; Ugt2b8; UGT2B9; UGTB2B9
UniProt ID: (Human) P16662, (Rat) Q62789
Entrez Gene ID: (Human) 7364, (Rat) 286989
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