The UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.
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Protein Aliases: 3,4-catechol estrogen specific; 3,4-catechol estrogen-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B7; UDP glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B9; UDP-glucuronyltransferase, family 2, beta-7; UDPGT 2B7; UDPGT 2B9; UDPGTh 2; UDPGTh-2
Gene Aliases: UDPGT 2B9; UDPGT2B7; UDPGTH2; UGT2B7; UGT2B9; UGTB2B9
UniProt ID: (Human) P16662
Entrez Gene ID: (Human) 7364