The UGTs serve a major role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. UGT2B7 has unique specificity for 3,4-catechol estrogens and estriol, suggesting that it may play an important role in regulating the level and activity of these potent estrogen metabolites. Its subcellular location is the microsome.
Protein Aliases: 3,4-catechol estrogen specific; 3,4-catechol estrogen-specific UDPGT; UDP glucuronosyltransferase 2 family, polypeptide B7; UDP glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B7; UDP-glucuronosyltransferase 2B9; UDP-glucuronyltransferase, family 2, beta-7; UDPGT 2B7; UDPGT 2B9; UDPGTh 2; UDPGTh-2
Gene Aliases: UDPGT 2B9; UDPGT2B7; UDPGTH2; UGT2B7; UGT2B9; UGTB2B9
UniProt ID: (Human) P16662
Entrez Gene ID: (Human) 7364