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Wnt6 Polyclonal Antibody
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Product Details
BS-6135R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human Wnt6, amino acids 281-365.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is overexpressed in cervical cancer cell line and strongly coexpressed with another family member, WNT10A, in colorectal cancer cell line. The gene overexpression may play key roles in carcinogenesis. This gene and the WNT10A gene are clustered in the chromosome 2q35 region. The protein encoded by this gene is 97% identical to the mouse Wnt6 protein at the amino acid level.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Mutations: 918:OK; Protein Wnt-6; unnamed protein product; wingless-related MMTV integration site 6; wingless-type MMTV integration site family, member 6
Gene Aliases: AA409270; Wnt-6; WNT6
UniProt ID: (Human) Q9Y6F9, (Mouse) P22727
Entrez Gene ID: (Human) 7475, (Rat) 316526, (Mouse) 22420
branching involved in ureteric bud morphogenesis
axis specification
positive regulation of gene expression
Wnt signaling pathway
neuron differentiation
odontogenesis of dentin-containing tooth
cell fate commitment
positive regulation of transcription, DNA-templated
canonical Wnt signaling pathway
epithelial-mesenchymal cell signaling
cornea development in camera-type eye
positive regulation of tooth mineralization
cellular response to retinoic acid
nephron tubule formation
nephron tubule development
biological_process
signal transduction
cell-cell signaling
multicellular organism development
organ morphogenesis
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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