cGMP Chemicals, Process Liquids, and Buffers

Chemicals, process liquids, and buffers for workflows that demand strict quality and regulatory standards

Your biologics start with the right chemicals. We offer multi-compendial chemicals, process liquids, and buffers manufactured to GMP standards and used in development and manufacturing across modalities—monoclonal antibodies (mAbs) and variants, cell and gene therapies, mRNA therapeutics, and other advanced biologics. 

 

Available in scalable volumes ranging from sample to bulk sizes 

Accessible in USP, EP, and other GMP multi-compendial grades 

Trusted global network of suppliers and manufacturers

Integrable supply chain management services 

We aim to go beyond dependable supply. Our portfolio supports the lot-to-lot consistency, material traceability, and regulatory-grade documentation required for both upstream and downstream operations, facilitating reproducible process performance and predictable product quality from R&D through commercial scale-up. Backed by rigorous quality systems and a network of trusted manufacturers and suppliers, we help reduce material-related variability and accelerate operations to empower you to focus on process design, scale-up, and delivering safe, effective biologic therapies.

Up to 90 days of storage at no additional cost

When you purchase your chemicals, process liquids, and buffers through us, up to 90 days of storage are at no additional cost. This offer allows you to take advantage of our cGMP- and GDP-compliant storage solutions while optimizing your facility space and resources. We can also store your raw materials beyond the 90-day period.

Learn how raw material quality decisions can enhance scale-up success

This whitepaper offers strategies for cell-based manufacturing, including process optimization, regulatory compliance, and risk management, to help enhance manufacturing efficiency and maintain product quality.

Stay informed with supply and market insights

Get timely chemical supply assurance insights to optimize your bioprocesses. Stay ahead with curated updates from the Chemical Supply Insights newsletter.
 

Global network

Our broad portfolio consists of multi-compendial chemicals, process liquids, and buffers from a global network of trusted manufacturers and suppliers as well as our own Gibco feeds, supplements, process liquids, and buffers. Available in dry and liquid formats starting at 1 kg and 100 mL sample sizes to bulk sizes, our products are supported by rigorous supplier qualification, comprehensive quality documentation, and global logistics—promoting regulatory-compliant sourcing and integration into development and manufacturing workflows.


Integration across bioprocessing and manufacturing workflows

We supply a comprehensive range of multi-compendial chemicals, process liquids, and buffers engineered for compatibility and performance across bioprocessing workflows—from cell culture and upstream processing through purification, formulation, and final fill. Each material is produced and qualified to meet the physical, chemical, and microbiological standards essential for reliable, reproducible results in regulated environments.

 

Whether you are scaling a process from development to commercial production or maintaining a validated manufacturing process, our portfolio and support infrastructure help you achieve quality assurance, regulatory readiness, and operational efficiency—enabling faster, more confident progression from lab to market.

Explore bioprocessing downstream calculators to facilitate your planning steps

Why choose Thermo Fisher?

Thermo Fisher is a trusted collaborator for bioprocessors—combining deep knowledge, a broad portfolio, and a steadfast commitment to customer success to deliver exceptional sourcing and procurement experiences. Formerly Doe & Ingalls Management, LLC, we continue to uphold the same high standards of quality and service in chemical, process liquid and buffer management so you can focus on innovating and producing high-impact biologics.

 

Contact us today to learn more about how we can add value to your bioprocesses and supply chain operations. Let us help you achieve operational excellence.

Industry engagement and commitment to excellence

As proud members of chemical industry associations, we support and help shape global standards, strengthen regulatory alignment, and drive innovation to enhance compliance, transparency, and operational excellence.


Supply management support for chemicals, process liquids, and buffers

A reliable, compliant supply chain is essential for bioprocessing success. Through our supply chain management team, bioprocessors can gain secure and efficient delivery of cGMP chemicals, process liquids, and buffers—helping enable uninterrupted operations and consistent product quality across operations.

 

Comprehensive supply chain services 

Thermo Fisher supply chain management teams can help streamline key operational areas, including:

Sourcing and Procurement

Enable your reliable supply of multi-compendial chemicals, process liquids, and buffers through our specialized cGMP chemicals and supply chain team.

 

cGMP Storage

Protect your investments in high-quality raw materials with an added layer of security at our ISO 9001-, cGMP- and GDP-compliant storage facilities.

 

Vendor Managed Inventory

Build supply continuity with regulatory-compliant storage, tracking, and conditions for your cGMP chemicals, process liquids, and buffers.

 

Supply chain management capabilities

Learn more about the rest of the capabilities we offer, including distribution, assurance of supply, and warehouse efficiency services. 

 

These end-to-end supply chain solutions for cGMP materials encompass qualified sourcing, strategic procurement, centralized inventory and storage, validated sampling, container take-back and recycling, and tailored cost-optimization services. This infrastructure allows you to reduce material variability, minimize waste and supply interruptions, and lower total cost of ownership—while aiming to maintain compliance, protect patient safety, and facilitate scalable chemical sourcing and material management across regions and production scales.

 

Explore our supply chain services for solutions to help you advance your biologics manufacturing with greater confidence and control. 
 


Intended use of the products mentioned on this page vary. For specific intended use statements please refer to the product label.