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Proteintech
BBS4 Polyclonal Antibody
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Product Details
12766-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
BBS4 Fusion Protein Ag3430 (1-351 aa encoded by BC027624)
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAEERVATR TQFPVSTESQ KPRQKKAPEF PILEKQNWLI HLHYIRKDYE ACKAVIKEQL QETQGLCEYA IYVQALIFRL EGNIQESLEL FQTCAVLSPQ SADNLKQVAR SLFLLGKHKA AIEVYNEAAK LNQKDWEISH NLGVCYIYLK QFNKAQDQLH NALNLNRHDL TYIMLGKIHL LEGDLDKAIE VYKKAVEFSP ENTELLTTLG LLYLQLGIYQ KAFEHLGNAL TYDPTNYKAI LAAGSMMQTH GDFDVALTKY RVVACAVPES PPLWNNIGMC FFGKKKYVAA ISCLKRANYL APFDWKILYN LGLVHLTMQQ YASAFHFLSA AINFQPKMGE LYMLLAVALT NL (1-351 aa encoded by BC027624)
Target Information
BBS4 contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyglucosamine transferase. Mutations in the gene encoding this protein have been observed in patients with Bardet-Biedl syndrome type 4. BBS4 may play a role in pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Bardet-Biedl syndrome 4 homolog; Bardet-Biedl syndrome 4 protein; Bardet-Biedl syndrome 4 protein homolog; BBS4; BBSome complex member BBS4; unnamed protein product
Gene Aliases: AW537059; AW742241; BBS4; D9Ertd464e
UniProt ID: (Human) Q96RK4, (Mouse) Q8C1Z7
Entrez Gene ID: (Human) 585, (Mouse) 102774, (Rat) 300754
microtubule cytoskeleton organization
mitotic cytokinesis
neuron migration
leukocyte homeostasis
B cell homeostasis
neural tube closure
retina homeostasis
heart looping
lymphocyte homeostasis
myeloid cell homeostasis
negative regulation of systemic arterial blood pressure
centrosome cycle
spermatid development
sensory perception
visual perception
sensory perception of smell
protein localization
gene expression
negative regulation of gene expression
protein transport
Wnt signaling pathway
dendrite development
regulation of lipid metabolic process
ventricular system development
striatum development
hippocampus development
cerebral cortex development
cell projection organization
adult behavior
negative regulation of actin filament polymerization
melanosome transport
regulation of cytokinesis
leptin-mediated signaling pathway
protein localization to organelle
erythrocyte homeostasis
microtubule anchoring at centrosome
social behavior
photoreceptor cell outer segment organization
negative regulation of appetite by leptin-mediated signaling pathway
positive regulation of multicellular organism growth
response to leptin
fat cell differentiation
photoreceptor cell maintenance
positive regulation of cilium assembly
retinal rod cell development
brain morphogenesis
homeostasis of number of cells
sensory processing
maintenance of protein location in nucleus
regulation of stress fiber assembly
cilium morphogenesis
regulation of cilium beat frequency involved in ciliary motility
face development
adipose tissue development
fat pad development
protein localization to cilium
protein localization to centrosome
sperm flagellum assembly
regulation of nonmotile primary cilium assembly
protein localization to photoreceptor outer segment
non-motile cilium assembly
transport
metabolic process
negative regulation of GTPase activity
nonmotile primary cilium assembly
cilium assembly
centrosome organization
biological_process
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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