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Proteintech
Carboxypeptidase E Polyclonal Antibody
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Product Details
13710-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Carboxypeptidase E Fusion Protein Ag4647 (126-476 aa encoded by BC033866)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: FLAQYLCNE YQKGNETIVN LIHSTRIHIM PSLNPDGFEK AASQPGELKD WFVGRSNAQG IDLNRNFPDL DRIVYVNEKE GGPNNHLLKN MKKIVDQNTK LAPETKAVIH WIMDIPFVLS ANLHGGDLVA NYPYDETRSG SAHEYSSSPD DAIFQSLARA YSSFNPAMSD PNRPPCRKND DDSSFVDGTT NGGAWYSVPG GMQDFNYLSS NCFEITVELS CEKFPPEETL KTYWEDNKNS LISYLEQIHR GVKGFVRDLQ GNPIANATIS VEGIDHDVTS AKDGDYWRLL IPGNYKLTAS APGYLAITKK VAVPYSPAAG VDFELESFSE RKEEEKEELM EWWKMMSETL NF (126-476 aa encoded by BC033866)
Target Information
This gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: carbocypeptidase E; Carboxypeptidase E; Carboxypeptidase H; CarboxypeptidaseE; CarboxypeptidaseH; CBPE; cobalt-stimulated chromaffin granule carboxypeptidase; CPE; CPH; Cph 1; Enkephalin convertase; epididymis secretory sperm binding protein; insulin granule-associated carboxypeptidase; Prohormone-processing carboxypeptidase; unnamed protein product
Gene Aliases: BDVS; CARBE; CPE; CPH; Cph-1; Cph1; fat; IDDHH; R74677
UniProt ID: (Human) P16870, (Rat) P15087, (Mouse) Q00493
Entrez Gene ID: (Human) 1363, (Rat) 25669, (Mouse) 12876
cardiac left ventricle morphogenesis
proteolysis
peptide metabolic process
cell communication
neuropeptide signaling pathway
protein localization
Wnt signaling pathway
protein processing
signaling
insulin processing
peptide hormone secretion
protein localization to secretory granule
protein modification process
protein localization to membrane
peptide hormone processing
enkephalin processing
peptide catabolic process
negative regulation of branching morphogenesis of a nerve
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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