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NeoBiotechnologies
TACSTD2/TROP2 (Epithelial Marker) Recombinant Mouse Monoclonal Antibody (rTACSTD2/9326)
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Product Details
4070-MSM12-P0
Product Specifications
Species Reactivity
Human
Host/Isotype
Mouse
/ IgG2b, kappa
Expression System
CHO cells
Class
Recombinant Monoclonal
Type
Antibody
Clone
rTACSTD2/9326
Immunogen
Recombinant fragment of human TACSTD2 protein (around aa 31-274).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
200 µg/mL
Amount
20 µg
Purification
Protein A
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
4°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Positive Control:HT29 cells. Human breast or colon carcinoma.
Cellular Location: Cell surface.
Target Information
TROP2 is a carcinoma-associated antigen defined by the monoclonal antibody GA733. This antigen is a member of a family including at least two type I membrane proteins. It transduces an intracellular calcium signal and acts as a cell surface receptor. Mutations of its gene result in gelatinous drop-like corneal dystrophy, an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 40kD glycoprotein, identified by monoclonal antibody GA733; cell surface glycoprotein Trop-2; cell surface glycoprotein TROP2; epithelial glycoprotein-1; GA733; gastrointestinal tumor-associated antigen GA7331; membrane component, chromosome 1, surface marker 1; pancreatic carcinoma marker protein GA733-1; pancreatic carcinoma marker protein GA7331; TACD2; TACSTD2; trophoblast cell surface antigen 2; unnamed protein product
Gene Aliases: EGP-1; EGP1; GA733-1; GA7331; GP50; M1S1; TROP2
UniProt ID: (Human) P09758
Entrez Gene ID: (Human) 4070
visual perception
negative regulation of epithelial cell migration
regulation of epithelial cell proliferation
negative regulation of stress fiber assembly
ureteric bud morphogenesis
negative regulation of branching involved in ureteric bud morphogenesis
negative regulation of substrate adhesion-dependent cell spreading
negative regulation of ruffle assembly
negative regulation of cell motility
positive regulation of stem cell differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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