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Invitrogen
Annexin V Monoclonal Antibody (C13)
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FIGURE: 1 / 16
Annexin V Antibody (MA5-41552) in ICC/IF
Immunofluorescence analysis of Annexin V was performed using 70-80% confluent log phase U-87 MG cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 45 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Annexin V Monoclonal Antibody (C13) (Product # MA5-41552, 1:100) in 0.1% BSA, incubated at 4 degree cel... View More
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-41552
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Bovine,
Dog,
Horse,
Human,
Mouse,
Sheep,
Pig,
Rabbit
Host/Isotype
Mouse
/ IgG1, kappa
Class
Monoclonal
Type
Antibody
Clone
C13
Immunogen
Recombinant protein Annexin V. The antigen corresponds to amino acid range 1-320 of the target protein.
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
200 µg
Purification
Protein A/G
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.05% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Target Information
The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anchorin CII; annexin 5; annexin V; annexin V (endonexin II); annexin-5; anticoagulant precursor (5' end put.); putative; ANXA5; calphobindin I; CBP-I; endonexin II; epididymis secretory protein Li 7; lipocortin V; lipocortin-V; PAP-I; placental anticoagulant protein 4; placental anticoagulant protein I; PP4; thromboplastin inhibitor; unnamed protein product; VAC-alpha; vascular anticoagulant-alpha
Gene Aliases: ANX5; CPB-I; ENX2; HEL-S-7; PP4; RPRGL3; VAC-alph
UniProt ID: (Human) P08758, (Mouse) P48036
Entrez Gene ID: (Human) 308, (Horse) 100072241, (Bovine) 281626, (Dog) 476094, (Rabbit) 100342904, (Pig) 100521982, (Sheep) 101114445, (Mouse) 11747
phosphatidylserine binding
phospholipase inhibitor activity
calcium ion binding
protein binding
phospholipid binding
calcium-dependent phospholipid binding
heparin binding
chondroitin sulfate binding
calcium-transporting ATPase activity
peptide hormone binding
receptor tyrosine kinase binding
identical protein binding
calcium-binding protein
signal transduction
negative regulation of apoptotic process
negative regulation of coagulation
blood coagulation
negative regulation of sequestering of calcium ion
negative regulation of blood coagulation
positive regulation of apoptotic process
response to calcium ion
calcium ion transmembrane transport
cellular response to gonadotropin-releasing hormone
regulation of sperm motility
negative regulation of prolactin secretion
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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