Search
Invitrogen
UBE2L3 Recombinant Rabbit Monoclonal Antibody (24GB1875)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 4
UBE2L3 Antibody (MA5-57812) in ICC/IF
Immunocytochemical staining of UBE2L3 in HepG2 cells using UBE2L3 Recombinant Monoclonal Antibody (Product # MA5-57812) at a 1:1,1000 dilution. Nuclei were stained blue with DAPI; UBE2L3 was stained magenta with Alexa Fluor® 647. Images were taken using Leica stellaris 5. Protein abundance based on laser Intensity and smart gain: Medium. Scale bar: 20 μm.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
MA5-57812
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Expression System
HEK293F
Class
Recombinant Monoclonal
Type
Antibody
Clone
24GB1875
Immunogen
A synthesized peptide derived from human UBE2L3 (aa 130-154)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Dry ice (international)
RRID
Target Information
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). UBE2L3 is a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: E2 ubiquitin-conjugating enzyme L3; UBE2L3; ubiquitin carrier protein L3; ubiquitin conjugating enzyme; ubiquitin conjugating enzyme E2L 3; ubiquitin-conjugating enzyme 7; ubiquitin-conjugating enzyme E2-F1; ubiquitin-conjugating enzyme UBCH7; ubiquitin-protein ligase L3; unnamed protein product
Gene Aliases: E2-F1; L-UBC; Ubce7; UBCH7; UbcM4; UbcR7
UniProt ID: (Human) P68036, (Mouse) P68037
Entrez Gene ID: (Human) 7332, (Mouse) 22195, (Rat) 363836
protein polyubiquitination
regulation of transcription, DNA-templated
ubiquitin-dependent protein catabolic process
cell proliferation
protein ubiquitination
positive regulation of protein ubiquitination
protein modification by small protein conjugation
protein modification process
cell cycle phase transition
positive regulation of transcription, DNA-templated
protein K11-linked ubiquitination
cellular response to steroid hormone stimulus
cellular response to glucocorticoid stimulus
positive regulation of establishment of protein localization to mitochondrion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support