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MAP2K1 (MEK1) [S218D] [S222D] Recombinant Human Protein

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MAP2K1 (MEK1) kinse is a dual-specific protein kinase that functions in mitogen-activated protein kinase (MAPK) cascades, controlling cell growth and differentiation. MAP2K1 is activated by a wide variety of growth factors and cytokines and also by membrane-dependent depolarization and calcium influx. This mutant has been activated by subsituting serines 218 and 222 with aspartic acid to mimic the phosphorylated state.
For Research Use Only. Not for use in diagnostic procedures.


Mass: 10 µg
Gene ID: 5604
Species: Human
Target Gene: Mitogen-activated protein kinase kinase 1
Gene Aliases: MAP2K1 (MEK1) S218D S222D
Kinase Group: Ser⁄Thr Kinases: STE Group
Product Size: 10 µg
Protein Family: Kinases & Inhibitors
Protein Subtype: Serine⁄Threonine Kinases
Accession Number: NP_002746, S218D, S222D
Molecular Weight: 49.2 kDa
Research Category: Signal Transduction
Validated Application: Kinase Assay
Protein Tag or Fusion: His Tag
Tag Position: N-Terminal
Expression: Baculovirus
Kinase Family: STE7 Kinase Family
Protein Form: Full Length, Recombinant
Shipping Condition: Dry Ice

Contents & storage

Storage Buffer: 50 mM Tris, pH 7.5, 150 mM NaCl, 0.05 mM EDTA, 0.05% NP-40, 1mM DTT, 50% glycerol
Store at -80°C. At first use, aliquot and store at -80°C to avoid multiple freeze-thaws.


Manuals & protocols

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