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Invitrogen
NPY Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA1-27980
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Guinea pig
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SDLLMRESTENAPRTR
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Protein G
Storage buffer
PBS
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: neuropeptide Y precursor; Neuropeptide-Y; OTTHUMP00000201947; pro-neuropeptide Y-like; unnamed protein product
Gene Aliases: 0710005A05Rik; NPY02; RATNPY; RATNPY02
UniProt ID: (Mouse) P57774, (Rat) P07808
Entrez Gene ID: (Mouse) 109648, (Rat) 24604
response to yeast
negative regulation of acute inflammatory response to antigenic stimulus
G-protein coupled receptor signaling pathway
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
neuropeptide signaling pathway
chemical synaptic transmission
feeding behavior
regulation of blood pressure
positive regulation of cell proliferation
adult feeding behavior
positive regulation of cell-substrate adhesion
antibacterial humoral response
antifungal humoral response
central nervous system neuron development
cerebral cortex development
neuron projection development
positive regulation of appetite
regulation of nerve growth factor production
monocyte activation
drinking behavior
innate immune response
regulation of nitric oxide biosynthetic process
negative regulation of blood pressure
positive regulation of dopamine metabolic process
short-day photoperiodism
developmental growth
defense response to Gram-negative bacterium
defense response to Gram-positive bacterium
antimicrobial humoral immune response mediated by antimicrobial peptide
positive regulation of ERK1 and ERK2 cascade
regulation of presynaptic cytosolic calcium ion concentration
synaptic signaling via neuropeptide
positive regulation of eating behavior
regulation of synaptic vesicle exocytosis
positive regulation of somatostatin secretion
negative regulation of somatostatin secretion
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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