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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: HESFKGYQPY EFTTLKSLQD PMKKLVEKEE KKKINQQEST DAAVQEPSQL ISLEEENQRK ESSSFK
Highest antigen sequence indentity to the following orthologs: Rat - 77%, Mouse - 70%.
This gene encodes a protein with an arfaptin homology domain that is found both in the cytosol and as membrane-bound form on the Golgi complex and immature secretory granules. This protein is believed to be an autoantigen in insulin-dependent diabetes mellitus and primary Sjogren's syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 69 kDa islet cell autoantigen; ICA69; ICAp69; Islet cell autoantigen 1; Islet cell autoantigen p69
Gene Aliases: ICA1
Entrez Gene ID: (Human) 3382
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