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Invitrogen
TXNDC3 Polyclonal Antibody
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Product Details
PA5-139787
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NME8. Recombinant protein control fragment (Product #RP-108790).
Conjugate
Form
Liquid
Concentration
0.8 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: TKAGFIIEAE HKTVLTEEQV VNFYSRIADQ RDFEEFVSFM TSGLSYILVV SQGSKHNPPS EETEPQTDTE PNERSEDQPE VEAQVTPGMM KNKQDSLQEY LE
Highest antigen sequence indentity to the following orthologs: Mouse - 50%, Rat - 43%.
Target Information
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3'-5' exonuclease NME8; epididymis secretory protein Li 99; NDK8; NM23-H8; NME/NM23 family member 8; Nucleoside diphosphate kinase 8; Protein kinase NME8; Protein NME8; Putative 3'-5'-DNA exonuclease NDK8; similar to nm23/dynein; sperm-specific thioredoxin 2; Spermatid-specific thioredoxin-2; Sptrx-2; thioredoxin domain containing 3 (spermatozoa); Thioredoxin domain-containing protein 3; unnamed protein product
Gene Aliases: CILD6; DNAI8; HEL-S-99; NM23-H8; NME8; sptrx-2; SPTRX2; TXNDC3
UniProt ID: (Human) Q8N427
Entrez Gene ID: (Human) 51314
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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