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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • C1QC Antibodies

          Invitrogen

          C1QC Polyclonal Antibody

          View all (7) C1QC antibodies

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          Cite C1QC Polyclonal Antibody

          • Antibody Testing Data (4)
          C1QC Antibody in Immunohistochemistry (IHC)
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          C1QC Antibody in Immunohistochemistry (IHC)
          Group 53 Created with Sketch.

          FIGURE: 1 / 4

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          C1QC Antibody (PA5-51583) in IHC

          Immunohistochemical staining of C1QC in human lymphoid tissues using C1QC Polyclonal Antibody (Product # PA5-51583) shows moderate cytoplasmic positivity in non-germinal center cells. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          C1QC Antibody in Immunohistochemistry (IHC)
          C1QC Antibody in Immunohistochemistry (IHC)
          C1QC Antibody in Immunohistochemistry (IHC)
          C1QC Antibody in Immunohistochemistry (IHC)
          C1QC Polyclonal Antibody

          Product Details

          PA5-51583

          Applications
          Tested Dilution
          Publications

          Immunohistochemistry (Paraffin) (IHC (P))

          1:200-1:500
          -
          Product Specifications

          Species Reactivity

          Human

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Recombinant protein corresponding to Human C1QC. Recombinant protein control fragment (Product #RP-95389).
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.1 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.2, with 40% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2638957

          Product Specific Information

          Immunogen sequence: GIPGEPGEEG RYKQKFQSVF TVTRQTHQPP APNSLIRFNA VLTNPQGDYD TSTGKFTCKV PGLYYFVYHA SHTANLCVLL YRSGVKVVTF CGHTSKTNQV NSGGVLLRLQ VGEEVWLAVN DYYDMVGIQG SD

          Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 73%.

          Target Information

          This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          References (0)

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          Cite this product

          Bioinformatics

          Protein Aliases: Complement C1q subcomponent subunit C; complement component 1, q subcomponent, C chain; complement component 1, q subcomponent, gamma polypeptide

          View more View less

          Gene Aliases: C1Q-C; C1QC; C1QG

          View more View less

          UniProt ID: (Human) P02747

          View more View less

          Entrez Gene ID: (Human) 714

          View more View less

          Function(s)
          serine-type endopeptidase activity
          Process(es)
          proteolysis immune response complement activation complement activation, classical pathway negative regulation of granulocyte differentiation innate immune response negative regulation of macrophage differentiation
          It has to be done as per old AB suggested Products section.
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          Performance Guarantee

          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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