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Invitrogen
eIF4ENIF1 Polyclonal Antibody
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Product Details
PA5-51680
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human eIF4ENIF1. Recombinant protein control fragment (Product #RP-91485).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: SPLEKDSDGL RLLGGRRIGS GRIISARTFE KDHRLSDKDL RDLRDRDRER DFKDKRFRRE FGDSKRVFGE RRRNDSYTEE EPEWFSAGPT SQSETIELTG FDDKILEEDH KGRKRTRRRT ASVKEGIVEC NGGVAEEDEV E
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 98%.
Target Information
The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: 2610509L04Rik; 4E-T; 4E-transporter; bA247I13.2; eIF4E transporter; Eukaryotic translation initiation factor 4E nuclear import factor 1; Eukaryotic translation initiation factor 4E transporter; FLJ21601; FLJ26551; nucleocytoplasmic shuttling protein; OTTHUMP00000063276; unnamed protein product
Gene Aliases: 4E-T; Clast4; EIF4ENIF1
UniProt ID: (Human) Q9NRA8
Entrez Gene ID: (Human) 56478
translation
regulation of translation
protein import into nucleus
protein transport
negative regulation of translation
stem cell population maintenance
neuron differentiation
gene silencing by RNA
cytoplasmic mRNA processing body assembly
miRNA mediated inhibition of translation
negative regulation of neuron differentiation
mRNA stabilization
nuclear export
positive regulation of nuclear-transcribed mRNA poly(A) tail shortening
negative regulation of deadenylation-dependent decapping of nuclear-transcribed mRNA
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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