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Invitrogen
MCT2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
PA5-52225
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human MCT2. Recombinant protein control fragment (Product #RP-88754).
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: GPNQTTSKSK NKTGKTEDDS SPKKIKTKKS TWEKVNKYLD FS
Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 45%.
Target Information
Tissues with few or no mitochondria, such as erythrocytes and tumor cells, depend largely on glycolysis to generate ATP. The major end products of glycolysis, pyruvate and lactate, must be eliminated from these cells to enable continued glycolytic flux and prevent toxic effects. H+/monocarboxylate transporters mediate the transport of lactate and pyruvate. Human MCT2 has a high affinity for the transport of pyruvate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: monocarboxylate transporter; solute carrier family 16 (monocarboxylate transporter), member 7; solute carrier family 16, member 7 (monocarboxylic acid transporter 2); unnamed protein product
Gene Aliases: MCT2
UniProt ID: (Human) O60669
Entrez Gene ID: (Human) 9194
pyruvate secondary active transmembrane transporter activity
protein binding
monocarboxylic acid transmembrane transporter activity
lactate transmembrane transporter activity
symporter activity
secondary active monocarboxylate transmembrane transporter activity
transmembrane transporter activity
identical protein binding
pyruvate transmembrane transporter activity
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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