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Invitrogen
TUB Polyclonal Antibody
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Product Details
PA5-53698
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TUB. Recombinant protein control fragment (Product #RP-91688).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: QSDHAQDAGE TAAGGGERPS GQDLRATMQR KGISSSMSFD EDEEDEEENS SSSSQLNSNT RPSSATSRKS VREAASAPSP TAPEQPVDVE VQDLEEFALR PAPQGITIKC RITRDKK
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 92%.
Target Information
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: tubby bipartite transcription factor; tubby homolog; tubby homologue; Tubby protein homolog; unnamed protein product
Gene Aliases: rd5; RDOB; TUB
UniProt ID: (Human) P50607
Entrez Gene ID: (Human) 7275
phagocytosis
phagocytosis, recognition
sensory perception of sound
regulation of G-protein coupled receptor protein signaling pathway
intraciliary transport
photoreceptor cell maintenance
positive regulation of phagocytosis
retina development in camera-type eye
protein localization to cilium
receptor localization to nonmotile primary cilium
protein localization to photoreceptor outer segment
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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