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Invitrogen
Adenylate Kinase 2 Polyclonal Antibody
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Product Details
PA5-53813
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human Adenylate Kinase 2. Recombinant protein control fragment (Product #RP-91714).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: LAENFCVCHL ATGDMLRAMV ASGSELGKKL KATMDAGKLV SDEMVVELIE KNLETPLCKN GFLLDGFPRT VRQAEMLDDL MEKRKEKLDS VIEFSIPDSL LIRR
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 96%.
Target Information
Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase, namely 1, 2, and 3, have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Adenylate kinase 2, mitochondrial; adenylate kinase 2, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03168}; adenylate kinase isoenzyme 2, mitochondrial; Adenylate monophosphate kinase; adenylate monophosphate kinase {ECO:0000255|HAMAP-Rule:MF_03168}; AK 2; AK 2 {ECO:0000255|HAMAP-Rule:MF_03168}; ATP-AMP transphosphorylase 2; ATP-AMP transphosphorylase 2 {ECO:0000255|HAMAP-Rule:MF_03168}; ATP:AMP phosphotransferase; ATP:AMP phosphotransferase {ECO:0000255|HAMAP-Rule:MF_03168}; testis secretory sperm-binding protein Li 220n; unnamed protein product
Gene Aliases: ADK2; Ak-2; AK2; D4Ertd220e
UniProt ID: (Human) P54819, (Rat) P29410, (Mouse) Q9WTP6
Entrez Gene ID: (Human) 204, (Rat) 24184, (Mouse) 11637
nucleobase-containing compound metabolic process
ADP biosynthetic process
nucleotide metabolic process
nucleoside monophosphate metabolic process
nucleobase-containing small molecule interconversion
AMP metabolic process
ATP metabolic process
nucleoside monophosphate phosphorylation
liver development
oxidative phosphorylation
brain development
dATP metabolic process
adenine metabolic process
nucleotide phosphorylation
response to thyroid hormone
phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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