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Invitrogen
TMEM70 Polyclonal Antibody
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Product Details
PA5-54717
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TMEM70. Recombinant protein control fragment (Product #RP-91012).
Conjugate
Form
Liquid
Concentration
0.05 mg/mL
Amount
5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: KGYVIRLYHE ATTDTYKAIT YNAMLAETST VFHQNDVKIP DAKHVFTTFY AKTKSLLVNP VLFPNREDYI HLMGYDKEEF ILYMEETSEE KRHKDDK
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 71%.
Target Information
TMEM70 is a recently identified mitochondrial protein that is thought to play a role in the biogenesis of the ATP synthase in higher eukaryotes. Mutations in this gene result in early neonatal onset of hypotonia, hypertrophic cardiomyopathy, lactic acidos and 3-methylglutaconic aciduria (3-MGC-uria), and usually cause death within the first six weeks of life, although some patients survive much longer. Little is known of the role of TMEM70, but it is conserved across multicellular eukaryotic organisms. It contains a conserved DUF1301 domain and two putative transmembrane regions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: mitochondrial complex V deficiency, nuclear type 1; Transmembrane protein 70, mitochondrial; unnamed protein product
Gene Aliases: MC5DN2; TMEM70
UniProt ID: (Human) Q9BUB7
Entrez Gene ID: (Human) 54968
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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